; Fri Jun 11 13:20:27 CEST 2010 ; ;+ (version "3.3.1") ;+ (build "Build 430") ([10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt] of file+text+source ) ([11_flexible+protein+ligand+rigid+body+docking.txt] of file+text+source ) ([11_flexible_protein_ligand_rigid_body_docking.txt] of file+text+source ) ([1_amphilicity_protein_ligand.txt] of file+text+source ) ([1_bending_energy_protein_ligand.txt] of file+text+source ) ([1_binding_site_volume_protein_ligand_interaction.txt] of file+text+source ) ([1_chemical_antagonism_protein_ligand.txt] of file+text+source ) ([1_clique+matching.txt] of file+text+source ) ([1_clique_matching.txt] of file+text+source ) ([1_co_agonist.txt] of file+text+source ) ([1_contact_surface_area_protein_ligand_interaction.txt] of file+text+source ) ([1_diastereoisomer_protein_ligand.txt] of file+text+source ) ([1_docking_output.txt] of file+text+source ) ([1_electric_dipole_moment_protein_ligand.txt] of file+text+source ) 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(knowtator_annotation_span "9726|9737") (knowtator_annotation_text "antagonists") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21793] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21794]) (knowtator_mention_class Interaction)) ([PL_annotations_Instance_21794] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21793]) (knowtator_annotation_creation_date "Thu May 27 17:48:07 CEST 2010") (knowtator_annotation_span "9882|9894") (knowtator_annotation_text "interactions") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21795] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21796]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_Instance_21796] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21795]) (knowtator_annotation_creation_date "Thu May 27 17:48:12 CEST 2010") (knowtator_annotation_span "9899|9906") (knowtator_annotation_text "agonist") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21797] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21798]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_Instance_21798] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21797]) (knowtator_annotation_creation_date "Thu May 27 17:48:15 CEST 2010") (knowtator_annotation_span "9918|9928") (knowtator_annotation_text "antagonist") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21799] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21800]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21801])) ([PL_annotations_Instance_21800] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21799]) (knowtator_annotation_creation_date "Thu May 27 17:48:18 CEST 2010") (knowtator_annotation_span "9947|9955") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21801] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21799])) ([PL_annotations_Instance_21802] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21803]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21804])) ([PL_annotations_Instance_21803] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21802]) (knowtator_annotation_creation_date "Thu May 27 17:49:22 CEST 2010") (knowtator_annotation_span "9802|9810") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21804] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21802])) ([PL_annotations_Instance_21805] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21806]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21807])) ([PL_annotations_Instance_21806] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21805]) (knowtator_annotation_creation_date "Thu May 27 17:49:36 CEST 2010") (knowtator_annotation_span "10110|10118") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21807] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21805])) ([PL_annotations_Instance_21808] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21809]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21810])) ([PL_annotations_Instance_21809] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21808]) (knowtator_annotation_creation_date "Thu May 27 17:49:42 CEST 2010") (knowtator_annotation_span "10361|10370") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21810] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21808])) ([PL_annotations_Instance_21811] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21812]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21813])) ([PL_annotations_Instance_21812] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21811]) (knowtator_annotation_creation_date "Thu May 27 17:49:45 CEST 2010") (knowtator_annotation_span "10401|10410") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21813] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21811])) ([PL_annotations_Instance_21814] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21815]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21816])) ([PL_annotations_Instance_21815] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21814]) (knowtator_annotation_creation_date "Thu May 27 17:49:57 CEST 2010") (knowtator_annotation_span "10673|10681") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21816] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21814])) ([PL_annotations_Instance_21817] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21818]) (knowtator_mention_class Interaction)) ([PL_annotations_Instance_21818] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21817]) (knowtator_annotation_creation_date "Thu May 27 17:50:07 CEST 2010") (knowtator_annotation_span "10908|10920") (knowtator_annotation_text "interactions") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21819] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21820]) (knowtator_mention_class Interaction)) ([PL_annotations_Instance_21820] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21819]) (knowtator_annotation_creation_date "Thu May 27 17:50:32 CEST 2010") (knowtator_annotation_span "11235|11247") (knowtator_annotation_text "interactions") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21821] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21822]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21823])) ([PL_annotations_Instance_21822] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21821]) (knowtator_annotation_creation_date "Thu May 27 17:50:43 CEST 2010") (knowtator_annotation_span "11395|11403") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21823] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21821])) ([PL_annotations_Instance_21824] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21825]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_Instance_21825] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21824]) (knowtator_annotation_creation_date "Thu May 27 17:50:51 CEST 2010") (knowtator_annotation_span "11536|11543") (knowtator_annotation_text "agonist") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21828] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21829]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21830])) ([PL_annotations_Instance_21829] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21828]) (knowtator_annotation_creation_date "Thu May 27 17:51:07 CEST 2010") (knowtator_annotation_span "11922|11930") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21830] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21828])) ([PL_annotations_Instance_21831] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21832]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21833])) ([PL_annotations_Instance_21832] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21831]) (knowtator_annotation_creation_date "Thu May 27 17:51:56 CEST 2010") (knowtator_annotation_span "11699|11707") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_endogenous_agonist.txt])) ([PL_annotations_Instance_21833] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21831])) ([PL_annotations_Instance_21834] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21835]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21836])) ([PL_annotations_Instance_21835] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21834]) (knowtator_annotation_creation_date "Thu May 27 17:57:02 CEST 2010") (knowtator_annotation_span "119|128") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21836] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21834])) ([PL_annotations_Instance_21837] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21838]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21839])) ([PL_annotations_Instance_21838] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21837]) (knowtator_annotation_creation_date "Thu May 27 17:57:35 CEST 2010") (knowtator_annotation_span "446|455") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21839] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21837])) ([PL_annotations_Instance_21840] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21841]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21842])) ([PL_annotations_Instance_21841] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21840]) (knowtator_annotation_creation_date "Thu May 27 17:57:40 CEST 2010") (knowtator_annotation_span "554|563") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21842] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21840])) ([PL_annotations_Instance_21843] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21844]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21845])) ([PL_annotations_Instance_21844] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21843]) (knowtator_annotation_creation_date "Thu May 27 17:57:57 CEST 2010") (knowtator_annotation_span "789|798") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21845] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21843])) ([PL_annotations_Instance_21846] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21847]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21848])) ([PL_annotations_Instance_21847] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21846]) (knowtator_annotation_creation_date "Thu May 27 17:58:06 CEST 2010") (knowtator_annotation_span "1049|1058") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21848] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21846])) ([PL_annotations_Instance_21849] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21850]) (knowtator_mention_class Interaction)) ([PL_annotations_Instance_21850] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21849]) (knowtator_annotation_creation_date "Thu May 27 17:58:13 CEST 2010") (knowtator_annotation_span "1098|1109") (knowtator_annotation_text "interaction") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21851] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21852]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_Instance_21852] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21851]) (knowtator_annotation_creation_date "Thu May 27 17:58:16 CEST 2010") (knowtator_annotation_span "1119|1140") (knowtator_annotation_text "physiological agonist") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21853] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21854]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21855])) ([PL_annotations_Instance_21854] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21853]) (knowtator_annotation_creation_date "Thu May 27 17:58:19 CEST 2010") (knowtator_annotation_span "1155|1164") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21855] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21853])) ([PL_annotations_Instance_21860] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21861]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21862])) ([PL_annotations_Instance_21861] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21860]) (knowtator_annotation_creation_date "Thu May 27 17:59:00 CEST 2010") (knowtator_annotation_span "1302|1310") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21862] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21860])) ([PL_annotations_Instance_21863] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21864]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21865])) ([PL_annotations_Instance_21864] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21863]) (knowtator_annotation_creation_date "Thu May 27 17:59:04 CEST 2010") (knowtator_annotation_span "1334|1342") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21865] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21863])) ([PL_annotations_Instance_21866] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21867]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21868])) ([PL_annotations_Instance_21867] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21866]) (knowtator_annotation_creation_date "Thu May 27 17:59:08 CEST 2010") (knowtator_annotation_span "1398|1406") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21868] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21866])) ([PL_annotations_Instance_21869] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21870]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21871])) ([PL_annotations_Instance_21870] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21869]) (knowtator_annotation_creation_date "Thu May 27 17:59:15 CEST 2010") (knowtator_annotation_span "1610|1619") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21871] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21869])) ([PL_annotations_Instance_21872] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21873]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21874])) ([PL_annotations_Instance_21873] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21872]) (knowtator_annotation_creation_date "Thu May 27 17:59:19 CEST 2010") (knowtator_annotation_span "1691|1700") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21874] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21872])) ([PL_annotations_Instance_21875] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21876]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21877])) ([PL_annotations_Instance_21876] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21875]) (knowtator_annotation_creation_date "Thu May 27 17:59:26 CEST 2010") (knowtator_annotation_span "1841|1849") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21877] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21875])) ([PL_annotations_Instance_21878] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21879]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_Instance_21880])) ([PL_annotations_Instance_21879] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_Instance_21878]) (knowtator_annotation_creation_date "Thu May 27 17:59:30 CEST 2010") (knowtator_annotation_span "1890|1899") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [1_protein_ligand_interactions_and_mode_of_action_and_physiological_agonist.txt])) ([PL_annotations_Instance_21880] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_Instance_21878])) ([PL_annotations_Instance_21881] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_Instance_21882]) 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of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_30050]) (knowtator_annotation_creation_date "Mon May 31 11:23:14 CEST 2010") (knowtator_annotation_span "1225|1232") (knowtator_annotation_text "ligands") (knowtator_annotation_text_source [1_interaction_prediction_protein_ligand.txt])) ([PL_annotations_test_Instance_30052] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_30053]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_30054])) ([PL_annotations_test_Instance_30053] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_30052]) (knowtator_annotation_creation_date "Mon May 31 11:23:17 CEST 2010") (knowtator_annotation_span "1272|1280") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_interaction_prediction_protein_ligand.txt])) ([PL_annotations_test_Instance_30054] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_30052])) ([PL_annotations_test_Instance_30055] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_30056]) (knowtator_mention_class Ligand)) ([PL_annotations_test_Instance_30056] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_30055]) (knowtator_annotation_creation_date "Mon May 31 11:23:21 CEST 2010") (knowtator_annotation_span "1332|1339") (knowtator_annotation_text "ligands") (knowtator_annotation_text_source [1_interaction_prediction_protein_ligand.txt])) ([PL_annotations_test_Instance_30059] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_30060]) (knowtator_mention_class binding+site)) ([PL_annotations_test_Instance_30060] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_30059]) (knowtator_annotation_creation_date "Mon May 31 11:24:07 CEST 2010") (knowtator_annotation_span "2054|2069") (knowtator_annotation_text "binding pockets") (knowtator_annotation_text_source [1_interaction_prediction_protein_ligand.txt])) ([PL_annotations_test_Instance_30061] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_30062]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_30063])) ([PL_annotations_test_Instance_30062] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_30061]) (knowtator_annotation_creation_date "Mon May 31 11:25:11 CEST 2010") (knowtator_annotation_span "323|331") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [1_interaction_prediction_protein_ligand.txt])) ([PL_annotations_test_Instance_30063] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_30061])) ([PL_annotations_test_Instance_301] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_300]) (knowtator_annotation_creation_date "Sat May 29 14:23:43 CEST 2010") (knowtator_annotation_span "15928|15941") (knowtator_annotation_text "binding\nsites") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_302] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_303]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_303] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_302]) (knowtator_annotation_creation_date "Sat May 29 14:23:48 CEST 2010") (knowtator_annotation_span "15963|15974") (knowtator_annotation_text "selectivity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_304] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_305]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_306])) ([PL_annotations_test_Instance_305] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_304]) (knowtator_annotation_creation_date "Sat May 29 14:23:53 CEST 2010") (knowtator_annotation_span "15996|16004") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_306] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_304])) ([PL_annotations_test_Instance_307] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_308]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_309])) ([PL_annotations_test_Instance_308] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_307]) (knowtator_annotation_creation_date "Sat May 29 14:23:57 CEST 2010") (knowtator_annotation_span "16024|16032") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_309] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_307])) ([PL_annotations_test_Instance_31] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_30]) (knowtator_annotation_creation_date "Sat May 29 13:47:42 CEST 2010") (knowtator_annotation_span "1328|1334") (knowtator_annotation_text "ligand") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_310] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_311]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_311] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_310]) (knowtator_annotation_creation_date "Sat May 29 14:24:08 CEST 2010") (knowtator_annotation_span "16200|16230") (knowtator_annotation_text "receptor-selective antagonists") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_312] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_313]) (knowtator_mention_class binding+site)) ([PL_annotations_test_Instance_313] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_312]) (knowtator_annotation_creation_date "Sat May 29 14:28:20 CEST 2010") (knowtator_annotation_span "16349|16371") (knowtator_annotation_text "receptor binding sites") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_314] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_315]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_315] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_314]) (knowtator_annotation_creation_date "Sat May 29 14:29:29 CEST 2010") (knowtator_annotation_span "16675|16683") (knowtator_annotation_text "agonists") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_316] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_317]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_317] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_316]) (knowtator_annotation_creation_date "Sat May 29 14:29:37 CEST 2010") (knowtator_annotation_span "17058|17065") (knowtator_annotation_text "agonist") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_318] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_319]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_319] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_318]) (knowtator_annotation_creation_date "Sat May 29 14:29:42 CEST 2010") (knowtator_annotation_span "17066|17074") (knowtator_annotation_text "activity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_32] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_33]) (knowtator_mention_class Interaction+Detection)) ([PL_annotations_test_Instance_320] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_321]) (knowtator_mention_class Ligand)) ([PL_annotations_test_Instance_321] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_320]) (knowtator_annotation_creation_date "Sat May 29 14:29:50 CEST 2010") (knowtator_annotation_span "17276|17283") (knowtator_annotation_text "ligands") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_322] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_323]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_323] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_322]) (knowtator_annotation_creation_date "Sat May 29 14:29:55 CEST 2010") (knowtator_annotation_span "17310|17318") (knowtator_annotation_text "activity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_324] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_325]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_326])) ([PL_annotations_test_Instance_325] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_324]) (knowtator_annotation_creation_date "Sat May 29 14:29:58 CEST 2010") (knowtator_annotation_span "17333|17341") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_326] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_324])) ([PL_annotations_test_Instance_327] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_328]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_328] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_327]) (knowtator_annotation_creation_date "Sat May 29 14:30:08 CEST 2010") (knowtator_annotation_span "17453|17475") (knowtator_annotation_text "functional selectivity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_329] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_330]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_331])) ([PL_annotations_test_Instance_33] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_32]) (knowtator_annotation_creation_date "Sat May 29 13:47:51 CEST 2010") (knowtator_annotation_span "1375|1380") (knowtator_annotation_text "X-ray") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_330] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_329]) (knowtator_annotation_creation_date "Sat May 29 14:30:13 CEST 2010") (knowtator_annotation_span "17518|17526") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_331] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_329])) ([PL_annotations_test_Instance_332] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_333]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_334])) ([PL_annotations_test_Instance_333] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_332]) (knowtator_annotation_creation_date "Sat May 29 14:30:17 CEST 2010") (knowtator_annotation_span "17542|17550") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_334] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_332])) ([PL_annotations_test_Instance_335] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_336]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_336] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_335]) (knowtator_annotation_creation_date "Sat May 29 14:30:24 CEST 2010") (knowtator_annotation_span "17628|17636") (knowtator_annotation_text "efficacy") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_337] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_338]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_339])) ([PL_annotations_test_Instance_338] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_337]) (knowtator_annotation_creation_date "Sat May 29 14:30:44 CEST 2010") (knowtator_annotation_span "17643|17652") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_339] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_337])) ([PL_annotations_test_Instance_34] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_35]) (knowtator_mention_class binding+site)) ([PL_annotations_test_Instance_340] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_341]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_341] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_340]) (knowtator_annotation_creation_date "Sat May 29 14:30:49 CEST 2010") (knowtator_annotation_span "17663|17671") (knowtator_annotation_text "activity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_342] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_343]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_344])) ([PL_annotations_test_Instance_343] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_342]) (knowtator_annotation_creation_date "Sat May 29 14:30:52 CEST 2010") (knowtator_annotation_span "17678|17687") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_344] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_342])) ([PL_annotations_test_Instance_345] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_346]) (knowtator_mention_class Ligand)) ([PL_annotations_test_Instance_346] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_345]) (knowtator_annotation_creation_date "Sat May 29 14:30:59 CEST 2010") (knowtator_annotation_span "17753|17760") (knowtator_annotation_text "ligands") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_347] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_348]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_348] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_347]) (knowtator_annotation_creation_date "Sat May 29 14:31:07 CEST 2010") (knowtator_annotation_span "17809|17832") (knowtator_annotation_text "functional \nselectivity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_349] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_350]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_351])) ([PL_annotations_test_Instance_35] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_34]) (knowtator_annotation_creation_date "Sat May 29 13:48:31 CEST 2010") (knowtator_annotation_span "1828|1839") (knowtator_annotation_text "active site") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_350] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_349]) (knowtator_annotation_creation_date "Sat May 29 14:31:15 CEST 2010") (knowtator_annotation_span "17846|17855") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_351] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_349])) ([PL_annotations_test_Instance_352] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_353]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_353] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_352]) (knowtator_annotation_creation_date "Sat May 29 14:31:20 CEST 2010") (knowtator_annotation_span "17888|17896") (knowtator_annotation_text "activity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_354] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_355]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_356])) ([PL_annotations_test_Instance_355] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_354]) (knowtator_annotation_creation_date "Sat May 29 14:31:24 CEST 2010") (knowtator_annotation_span "17903|17912") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_356] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_354])) ([PL_annotations_test_Instance_357] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_358]) (knowtator_mention_class Interaction+simulation)) ([PL_annotations_test_Instance_358] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_357]) (knowtator_annotation_creation_date "Sat May 29 14:32:30 CEST 2010") (knowtator_annotation_span "17974|17993") (knowtator_annotation_text "Molecular \nmodeling") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_359] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_360]) (knowtator_mention_class Interaction)) ([PL_annotations_test_Instance_36] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_37]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_360] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_359]) (knowtator_annotation_creation_date "Sat May 29 14:32:52 CEST 2010") (knowtator_annotation_span "18059|18070") (knowtator_annotation_text "interaction") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_361] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_362]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_Instance_362] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_361]) (knowtator_annotation_creation_date "Sat May 29 14:32:54 CEST 2010") (knowtator_annotation_span "18085|18093") (knowtator_annotation_text "agonists") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_363] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_364]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_365])) ([PL_annotations_test_Instance_364] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_363]) (knowtator_annotation_creation_date "Sat May 29 14:32:58 CEST 2010") (knowtator_annotation_span "18106|18114") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_365] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_363])) ([PL_annotations_test_Instance_368] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_369]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_Instance_370])) ([PL_annotations_test_Instance_369] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_368]) (knowtator_annotation_creation_date "Sat May 29 14:33:08 CEST 2010") (knowtator_annotation_span "18151|18159") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_37] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_36]) (knowtator_annotation_creation_date "Sat May 29 13:48:36 CEST 2010") (knowtator_annotation_span "1859|1880") (knowtator_annotation_text "substrate specificity") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_370] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_Instance_368])) ([PL_annotations_test_Instance_371] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_372]) (knowtator_mention_class Interaction)) ([PL_annotations_test_Instance_372] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_371]) (knowtator_annotation_creation_date "Sat May 29 14:33:11 CEST 2010") (knowtator_annotation_span "18179|18191") (knowtator_annotation_text "interactions") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_373] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_374]) (knowtator_mention_class Interaction)) ([PL_annotations_test_Instance_374] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_373]) (knowtator_annotation_creation_date "Sat May 29 14:33:15 CEST 2010") (knowtator_annotation_span "18219|18231") (knowtator_annotation_text "interactions") (knowtator_annotation_text_source [10_protein_ligand_interactions_selectivity_binding_selectivity_functional_selectivity.txt])) ([PL_annotations_test_Instance_375] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_Instance_376]) (knowtator_mention_class Interaction)) ([PL_annotations_test_Instance_376] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_Instance_375]) 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"interactions") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50720] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50721]) (knowtator_mention_class Ligand)) ([PL_annotations_test_termodynamics_Instance_50721] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50720]) (knowtator_annotation_creation_date "Thu Jun 10 12:46:48 CEST 2010") (knowtator_annotation_span "131|138") (knowtator_annotation_text "ligands") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50722] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50723]) (knowtator_mention_class Interaction)) ([PL_annotations_test_termodynamics_Instance_50723] of knowtator+annotation (knowtator_annotated_mention 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[PL_annotations_test_termodynamics_Instance_50742]) (knowtator_annotation_creation_date "Thu Jun 10 12:48:58 CEST 2010") (knowtator_annotation_span "1758|1770") (knowtator_annotation_text "binding\nsite") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50744] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50745]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_50745] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50744]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:10 CEST 2010") (knowtator_annotation_span "2020|2023") (knowtator_annotation_text "K(d") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50746] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50747]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_50747] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50746]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:14 CEST 2010") (knowtator_annotation_span "2069|2072") (knowtator_annotation_text "K(d") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50748] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50749]) (knowtator_mention_class Interaction)) ([PL_annotations_test_termodynamics_Instance_50749] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50748]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:22 CEST 2010") (knowtator_annotation_span "2259|2272") (knowtator_annotation_text "hydrogen bond") 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[PL_annotations_test_termodynamics_Instance_50752]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:33 CEST 2010") (knowtator_annotation_span "2368|2371") (knowtator_annotation_text "K(d") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50754] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50755]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_50755] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50754]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:39 CEST 2010") (knowtator_annotation_span "2492|2495") (knowtator_annotation_text "K(d") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50756] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50757]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_50757] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50756]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:47 CEST 2010") (knowtator_annotation_span "2636|2652") (knowtator_annotation_text "binding affinity") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50758] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50759]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_50759] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50758]) (knowtator_annotation_creation_date "Thu Jun 10 12:49:53 CEST 2010") (knowtator_annotation_span "2696|2699") (knowtator_annotation_text "K(d") 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[PL_annotations_test_termodynamics_Instance_50762]) (knowtator_annotation_creation_date "Thu Jun 10 12:50:05 CEST 2010") (knowtator_annotation_span "2892|2900") (knowtator_annotation_text "activity") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50764] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50765]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_50766])) ([PL_annotations_test_termodynamics_Instance_50765] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50764]) (knowtator_annotation_creation_date "Thu Jun 10 12:50:11 CEST 2010") (knowtator_annotation_span "2986|2991") (knowtator_annotation_text "motif") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50766] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_termodynamics_Instance_50764])) ([PL_annotations_test_termodynamics_Instance_50767] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50768]) (knowtator_mention_class binding+site)) ([PL_annotations_test_termodynamics_Instance_50768] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50767]) (knowtator_annotation_creation_date "Thu Jun 10 12:50:14 CEST 2010") (knowtator_annotation_span "3011|3023") (knowtator_annotation_text "binding site") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50769] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50770]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_50770] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50769]) (knowtator_annotation_creation_date "Thu Jun 10 12:50:25 CEST 2010") (knowtator_annotation_span "3259|3267") (knowtator_annotation_text "affinity") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50771] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50772]) (knowtator_mention_class Ligand)) ([PL_annotations_test_termodynamics_Instance_50772] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50771]) (knowtator_annotation_creation_date "Thu Jun 10 12:50:31 CEST 2010") (knowtator_annotation_span "3252|3258") (knowtator_annotation_text "ligand") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50773] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50774]) (knowtator_mention_class binding+site)) ([PL_annotations_test_termodynamics_Instance_50774] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50773]) (knowtator_annotation_creation_date "Thu Jun 10 13:07:58 CEST 2010") (knowtator_annotation_span "3283|3295") (knowtator_annotation_text "binding site") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50775] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50776]) (knowtator_mention_class Interaction+simulation)) ([PL_annotations_test_termodynamics_Instance_50776] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50775]) (knowtator_annotation_creation_date "Thu Jun 10 13:08:07 CEST 2010") (knowtator_annotation_span "3322|3341") (knowtator_annotation_text "lock and key' model") (knowtator_annotation_text_source [2_lock_and_key_model_protein_ligand.txt])) ([PL_annotations_test_termodynamics_Instance_50777] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50778]) (knowtator_mention_class Interaction)) ([PL_annotations_test_termodynamics_Instance_50778] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50777]) (knowtator_annotation_creation_date "Thu Jun 10 13:09:49 CEST 2010") (knowtator_annotation_span "293|305") (knowtator_annotation_text "interactions") (knowtator_annotation_text_source [2_modulator_protein_ligand_interactions.txt])) ([PL_annotations_test_termodynamics_Instance_50779] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50780]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_50781])) ([PL_annotations_test_termodynamics_Instance_50780] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50779]) (knowtator_annotation_creation_date "Thu Jun 10 13:09:52 CEST 2010") (knowtator_annotation_span "337|346") (knowtator_annotation_text "receptors") (knowtator_annotation_text_source [2_modulator_protein_ligand_interactions.txt])) ([PL_annotations_test_termodynamics_Instance_50781] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_termodynamics_Instance_50779])) ([PL_annotations_test_termodynamics_Instance_50782] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50783]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_50784])) ([PL_annotations_test_termodynamics_Instance_50783] of 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[PL_annotations_test_termodynamics_Instance_50787])) ([PL_annotations_test_termodynamics_Instance_50790] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_50791]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_50792])) ([PL_annotations_test_termodynamics_Instance_50791] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_50790]) (knowtator_annotation_creation_date "Thu Jun 10 13:10:28 CEST 2010") (knowtator_annotation_span "1359|1367") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [2_modulator_protein_ligand_interactions.txt])) ([PL_annotations_test_termodynamics_Instance_50792] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_termodynamics_Instance_50790])) ([PL_annotations_test_termodynamics_Instance_50793] of 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knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91026]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_91026] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91025]) (knowtator_annotation_creation_date "Fri Jun 11 13:15:11 CEST 2010") (knowtator_annotation_span "5935|5950") (knowtator_annotation_text "inverse\nagonist") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91027] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91028]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_91028] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91027]) (knowtator_annotation_creation_date "Fri Jun 11 13:15:16 CEST 2010") (knowtator_annotation_span "6036|6044") (knowtator_annotation_text "activity") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91029] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91030]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_91031])) ([PL_annotations_test_termodynamics_Instance_91030] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91029]) (knowtator_annotation_creation_date "Fri Jun 11 13:15:20 CEST 2010") (knowtator_annotation_span "6071|6079") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91031] of knowtator+string+slot+mention (knowtator_mention_slot 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([PL_annotations_test_termodynamics_Instance_91038] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91039]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_91040])) ([PL_annotations_test_termodynamics_Instance_91039] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91038]) (knowtator_annotation_creation_date "Fri Jun 11 13:15:35 CEST 2010") (knowtator_annotation_span "6299|6307") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91040] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_termodynamics_Instance_91038])) ([PL_annotations_test_termodynamics_Instance_91041] of knowtator+class+mention 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"6372|6387") (knowtator_annotation_text "inverse agonist") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91045] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91046]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_91047])) ([PL_annotations_test_termodynamics_Instance_91046] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91045]) (knowtator_annotation_creation_date "Fri Jun 11 13:15:53 CEST 2010") (knowtator_annotation_span "6402|6410") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91047] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_termodynamics_Instance_91045])) ([PL_annotations_test_termodynamics_Instance_91048] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91049]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_91050])) ([PL_annotations_test_termodynamics_Instance_91049] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91048]) (knowtator_annotation_creation_date "Fri Jun 11 13:15:57 CEST 2010") (knowtator_annotation_span "6441|6449") (knowtator_annotation_text "receptor") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91050] of knowtator+string+slot+mention (knowtator_mention_slot [PL_annotations_Slot_10009]) (knowtator_mentioned_in [PL_annotations_test_termodynamics_Instance_91048])) ([PL_annotations_test_termodynamics_Instance_91051] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91052]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_91052] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91051]) (knowtator_annotation_creation_date "Fri Jun 11 13:16:02 CEST 2010") (knowtator_annotation_span "6465|6477") (knowtator_annotation_text "conformation") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91053] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91054]) (knowtator_mention_class Protein) (knowtator_slot_mention [PL_annotations_test_termodynamics_Instance_91055])) ([PL_annotations_test_termodynamics_Instance_91054] of knowtator+annotation (knowtator_annotated_mention 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(knowtator_annotation_text "inverse\nagonist") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([PL_annotations_test_termodynamics_Instance_91058] of knowtator+class+mention (knowtator_mention_annotation [PL_annotations_test_termodynamics_Instance_91059]) (knowtator_mention_class Ligand+activity)) ([PL_annotations_test_termodynamics_Instance_91059] of knowtator+annotation (knowtator_annotated_mention [PL_annotations_test_termodynamics_Instance_91058]) (knowtator_annotation_creation_date "Fri Jun 11 13:17:47 CEST 2010") (knowtator_annotation_span "2830|2840") (knowtator_annotation_text "antagonist") (knowtator_annotation_text_source [3_protein_ligand_interactions_and_mode_of_action_and_inverse_agonist.txt])) ([Protein] of %3ASTANDARD-CLASS (%3ASLOT-CONSTRAINTS [PL_annotations_Instance_10008]))